Micronization of Taxifolin by Supercritical Antisolvent Process and Evaluation of Radical Scavenging Activity

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Micronization of Taxifolin by Supercritical Antisolvent Process and Evaluation of Radical Scavenging Activity

The aim of this study was to prepare micronized taxifolin powder using the supercritical antisolvent precipitation process to improve the dissolution rate of taxifolin. Ethanol was used as solvent and carbon dioxide was used as an antisolvent. The effects of process parameters, such as temperature (35-65 °C), pressure (10-25 MPa), solution flow rate (3-6 mL/min) and concentration of the liquid ...

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ژورنال

عنوان ژورنال: International Journal of Molecular Sciences

سال: 2012

ISSN: 1422-0067

DOI: 10.3390/ijms13078869